基底材料的拓?fù)湫蚊彩怯绊懠?xì)胞行為的重要因素之一,細(xì)胞與微納米結(jié)構(gòu)圖案表面相互作用研究在細(xì)胞生物學(xué)、再生醫(yī)學(xué)和組織工程領(lǐng)域具有重要的意義。材料表面微納米圖案化不但可以提供結(jié)構(gòu)模版,用以研究細(xì)胞對生長環(huán)境的響應(yīng)特性,而且可以為組織再生用支架和植入性器件的設(shè)計提供基礎(chǔ)數(shù)據(jù)。
微流控和圖型化技術(shù)在細(xì)胞生物學(xué)領(lǐng)域中的應(yīng)用具有重要的意義.
實驗結(jié)果顯示,細(xì)胞會根據(jù)材料基底表面的圖案結(jié)構(gòu)產(chǎn)生相應(yīng)的形變,而且這種形變響應(yīng)與圖案幾何形狀、尺寸,細(xì)胞伸展和基底表面的黏附蛋白濃度有關(guān)。在一定范圍內(nèi),圖案越大、越深,細(xì)胞形變越大；細(xì)胞伸展面積越大,形變越小：黏附蛋白可以促進(jìn)細(xì)胞伸展,從而使細(xì)胞形變減小.xonamicrofluidics品牌細(xì)胞微溝槽圖案流體培養(yǎng)板微米坑圖案能夠明顯促進(jìn)細(xì)胞在材料表面的黏附；xonamicrofluidics品牌細(xì)胞微溝槽圖案流體培養(yǎng)板微米溝槽圖案則對細(xì)胞具有接觸誘導(dǎo)效應(yīng),可以誘導(dǎo)細(xì)胞響應(yīng)所生長的微納米溝槽結(jié)構(gòu)進(jìn)行骨架重排,從而引起細(xì)胞取向行為變化.
品牌 貨號 產(chǎn)品名稱
xona Microfluidics snd150 神經(jīng)元突觸細(xì)胞微灌流系統(tǒng)
Standard Neuron Device (150 um microgroove barrier)
Cat.No: SND150
Size: ~ 22 mm – ~23mm
The 150 um neuron device with its shorter microgroove barrier is suitable for researchers who would like to isolate both axons and dendrites. It is also suitable for certain neuronal cultures that do not grow long processes.
Researchers who wish to study the early events of axonal and dendritic growth may also find the 150 um device useful. The 150 um device also offers the benefits of fluidic isolation and culture organization for transport studies.
xona microfluidics snd450 細(xì)胞微溝槽圖案流體培養(yǎng)板
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xona microfluidics RD150 細(xì)胞微溝槽圖案流體培養(yǎng)板
xona microfluidics RD450 細(xì)胞微溝槽圖案流體培養(yǎng)板
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